Gliomedin Antibody

Product Discontinued

Gliomedin Antibody Summary

• Immunogen: A synthetic peptide made to residues 160-176 of human CRG-L2.
• Specificity: Reacts with residues 160-176 [LVGKADEKASEHHSPQA] of human CRG-L2. This sequence is between the collagen domains (residues 29-88 and 89-149) and the olfactomedin domain (residues 189-433).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GLDN
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:100-1:2000
• Application Notes: This antibody has been tested in Western blot. The predicted MW is 48 kDa; however the protein runs above 50 kDa on gels and can form dimers. No other applications have been tested. Recommended Starting Dilution:* Western blot: 1:500-1:1,000 *The investigator should determine the optimal working dilution for a specific application. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Theoretical MW: 55 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Gliomedin Antibody

• CLOM
• collomin
• COLM
• colmedin
• CRGL2
• CRG-L2
• FLJ23917
• gliomedin
• UNC-112

Background

A novel gene, CRG-L2 (Cancer related gene-Liver 2) displays high expression in murine and human hepatocellular carcinomas (HCC). Its restricted expression in normal tissues and unique early upregulation during tumor development make CRG-L2 an excellent candidate as a new clinical marker of HCC.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GLDN
• Entrez:
  • 342035(Human)