GBL Antibody [Alexa Fluor® 405]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 405

GBL Antibody [Alexa Fluor® 405] Summary

• Immunogen: E. coli-derived recombinant human GβL
  Met1-Gly327
  Accession # Q9BVC4
• Specificity: Detects human, mouse, and rat G beta L in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for GBL Antibody [Alexa Fluor® 405]

• G protein beta subunit-like
• gable
• GbetaL
• GBL
• GBLPop3
• Lst8
• LST8MGC111011
• Mammalian lethal with SEC13 protein 8
• mLST8
• MTOR associated protein, LST8 homolog (S. cerevisiae)
• POP3
• Protein GbetaL
• target of rapamycin complex subunit LST8
• TORC subunit LST8
• WAT1

Background

G-protein beta -subunit-like (G beta L), also known as mLST8, is a subunit of the Target of Rapamycin (TOR) complex. G beta L contains 7 WD-40 repeats, and binds to the kinase domain of TOR in both the Raptor (Rapamycin-sensitive)-and Rictor (Rapamycin-insensitive)-containing complexes. G beta L is necessary for the full activation of the TOR kinase, and phosphorylation of many downstream proteins, including 4E-BP1 and p70^S6 kinase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.