GARNL1 Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: GARNL1 Antibody [NBP1-87982] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & mitochondria.

Immunohistochemistry-Paraffin: GARNL1 Antibody [NBP1-87982] - Staining of human cerebellum shows cytoplasmic positivity in Purkinje cells, cells in molecular layer and granular layer.

• Reactivity: Hu, Rt
• Applications: ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

GARNL1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit GARNL1 Antibody - BSA Free (NBP1-87982) is a polyclonal antibody validated for use in IHC and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: LVSCIQIRSEENMPGGGLSAGLASANSNVRIIVRDLSGKYSWDSAILYGPPPVSGLSEPTSFMLSLSHQEKPEEPPTSNECLEDITVKDGLSLQFKRFRETVPTWDTIRDEEDVLDELLQYLGVTSPECLQRTGISLNIPAPQPVCISE
• Predicted Species: Rat (90%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RALGAPA1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  GARNL1 Protein (NBP1-87982PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for GARNL1 Antibody - BSA Free

• DKFZp566D133
• DKFZp667F074
• GAP-related interacting protein to E12
• GARNL1p240
• GRIPEGAP-related-interacting partner to E12
• GTPase activating RANGAP domain-like 1
• GTPase activating Rap/RanGAP domain-like 1
• KIAA0884GTPase-activating Rap/Ran-GAP domain-like 1
• Ral GTPase activating protein, alpha subunit 1 (catalytic)
• ral GTPase-activating protein alpha subunit 1
• ral GTPase-activating protein subunit alpha-1
• RalGAPalpha1
• Tuberin-like protein 1
• TULIP1Tulip1

Background

Interacting partner of the transcription factor TCF3/isoform E12, mainly in the developing embryonicforebrain. May be an important transcriptional regulator of downstream target genes under the control of TCF3/E12, bydisrupting HLH dimer formation of TCF3/E12 with other proteins. May be involved in neuronal differentiation (Bysimilarity)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RALGAPA1