GADD45 alpha Antibody [Biotin]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Biotin

GADD45 alpha Antibody [Biotin] Summary

• Immunogen: E. coli-derived recombinant human GADD45 alpha
  Met1-Arg165
  Accession # P24522
• Specificity: Detects human GADD45 alpha in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: GADD45A
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for GADD45 alpha Antibody [Biotin]

• DDIT-1
• DDIT1growth arrest and DNA damage-inducible protein GADD45 alpha
• DNA damage-inducible transcript 1 protein
• DNA damage-inducible transcript-1
• GADD45 alpha
• GADD45a
• GADD45DNA-damage-inducible transcript 1
• growth arrest and DNA-damage-inducible 45 alpha
• growth arrest and DNA-damage-inducible, alpha

Background

GADD45A is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GADD45A