GABA-AR alpha 2 Antibody (RB23934)

Product Discontinued

GABA-AR alpha 2 Antibody (RB23934) Summary

• Immunogen: This GABRA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the C-terminal region of human GABRA2.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GABRA2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:10 - 1:50
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:10 - 1:50
  • Western Blot 1:1000
• Theoretical MW: 51.326 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Predicted to react with Bovine, Mouse and Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 0.32 mg/ml
• Purity: Protein A purified

Alternate Names for GABA-AR alpha 2 Antibody (RB23934)

• GABA A R alpha 2
• GABA(A) receptor subunit alpha-2
• GABAAR alpha 2
• GABAARa2
• GABRA2
• gamma-aminobutyric acid (GABA) A receptor, alpha 2
• gamma-aminobutyric acid receptor subunit alpha-2

Background

GABRA2 is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GABRA2
• Uniprot:
  • P47869(Human)