FYCO1 Antibody - Azide and BSA Free

Western Blot: FYCO1 Antibody [H00079443-B01P] - Analysis of FYCO1 expression in human colon.

Western Blot: FYCO1 Antibody [H00079443-B01P] - Analysis of FYCO1 expression in transfected 293T cell line by FYCO1 polyclonal antibody. Lane 1: FYCO1 transfected lysate(28.05 KDa). Lane 2: Non-transfected lysate.

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

FYCO1 Antibody - Azide and BSA Free Summary

• Immunogen: FYCO1 (AAH07218.1, 1 a.a. - 255 a.a.) full-length human protein. MNTKVTSDWYYARSPFLQPKLSSDIVGQLYELTEVQFDLASRGFDLDAAWPTFARRTLTTGSSAYLWKPPSRSSSMSSLVSSYLQTQEMVSNFDLNSPLNNEALEGFDEMRLELDQLEVREKQLQERMQQLDRENQELRAAVSQQGEQLQTERERGRTAAEDNVRLTCLVAELQKQWEVTQATQNTVKELQTCLQALELGAAEKEEDYHTALRRLESMLQPLAQELEATRDSLDKKNQHLASFPGWLAMALHVGD
• Specificity: FYCO1 - FYVE and coiled-coil domain containing 1,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: FYCO1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for FYCO1 Antibody - Azide and BSA Free

• DKFZp779K1152
• FLJ13335
• FYVE and coiled-coil domain containing 1
• FYVE and coiled-coil domain-containing protein 1
• MGC126517
• RUFY3
• RUN and FYVE domain containing 3
• ZFYVE7MGC126519
• Zinc finger FYVE domain-containing protein 7

Background

FYCO1, Fyve and Coiled-Coil domain-containing 1, is a gene that is lost in chromosomal deletions in nearly all types of solid tumors. FYCO1 forms a complex with LC3 and Rab7 that promotes microtubule plus end-directed transport of autophagic vesicles. It is possible that FYCO1 has membrane-tethering functions as well.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for FYCO1 Antibody (H00079443-B01P)(1)

Publication using H00079443-B01P

• Olsvik HL, Lamark T, Takagi K et al. FYCO1 Contains a C-terminally Extended, LC3A/B-preferring LC3-Interacting Region (LIR) Motif Required for Efficient Maturation of Autophagosomes During Basal Autophagy. J Biol Chem. 2015-10-14 [PMID: 26468287]

Bioinformatics

• Gene Symbol: FYCO1
• Entrez:
  • 79443(Human)
• Uniprot:
  • AAH07218.1(Human)