FVT1 Antibody - BSA Free

Western Blot: FVT1 Antibody [NBP2-14962] - Whole cell extract (30 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with FVT1 antibody [N2C3] (NBP2-14962) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

• Reactivity: Hu, Mu, Rt, Bv, Pm, RM
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

FVT1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit FVT1 Antibody - BSA Free (NBP2-14962) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human FVT1. The exact sequence is proprietary.
• Predicted Species: Mouse (92%), Rat (92%), Rhesus Macaque (99%), Bovine (91%), Chimpanzee (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KDSR
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:3000
• Theoretical MW: 36 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Xenopus laevis (81%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for FVT1 Antibody - BSA Free

• 3-ketodihydrosphingosine reductase
• DHSR
• EC 1.1.1.102,3-dehydrosphinganine reductase
• FLJ36555
• FLJ92680
• follicular lymphoma variant translocation 1
• Follicular variant translocation protein 1
• FVT-1
• FVT1KDS reductase
• SDR35C1
• short chain dehydrogenase/reductase family 35C, member 1

Background

The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: KDSR
• Uniprot:
  • Q06136(Human)