Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Bv, Pm, RM
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
The protein encoded by the FVT1 gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
2531 |
| Alternate Names |
- 3-ketodihydrosphingosine reductase
- DHSR
- EC 1.1.1.102,3-dehydrosphinganine reductase
- FLJ36555
- FLJ92680
- follicular lymphoma variant translocation 1
- Follicular variant translocation protein 1
- FVT-1
- FVT1KDS reductase
- SDR35C1
- short chain dehydrogenase/reductase family 35C, member 1
|
