FVT1 Products

Description

The protein encoded by the FVT1 gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy.

Bioinformatics

Entrez	2531 Human
Uniprot	Q06136 Human AAH08797 Human AAH08797.1 Human NP_002026 Human
Product By Gene ID	2531
Alternate Names	EC 1.1.1.102,3-dehydrosphinganine reductase Follicular variant translocation protein 1 short chain dehydrogenase/reductase family 35C, member 1 follicular lymphoma variant translocation 1 FLJ92680 SDR35C1 FLJ36555 DHSR FVT1KDS reductase FVT-1 3-ketodihydrosphingosine reductase

Bioinformatics Tool for FVT1

Discover related pathways, diseases and genes to FVT1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.