FUBP3 Antibody (24GB13150)

• Reactivity: Hu, Mu, Rt
• Applications: WB, Flow, ICC/IF, Mycoplasma
• Clone: 24GB13150
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

FUBP3 Antibody (24GB13150) Summary

• Description: Reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.
• Immunogen: Recombinant protein of human FUBP3 (Uniprot: Q96I24)
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: FUBP3
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Knockdown Validated
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for FUBP3 Antibody (24GB13150)

• far upstream element (FUSE) binding protein 3
• far upstream element-binding protein 3
• FBP3
• FLJ25229
• FUSE-binding protein 3

Background

Activation of FUSE, the far-upstream element, is required for the proper expression of the mammalian gene c-Myc in undifferentiated cells. The binding of FBP (FUSE-binding protein) to FUSE is necessary for c-Myc expression, indicating that FBP functions as a growth-dependent regulator of c-Myc expression. Isolated from proliferating HL60 cells, FBP, FBP2, and FBP3 comprise a family of single-stranded DNA-binding proteins that specifically bind to FUSE elements. The FBP transcription factors share a conserved central DNA-binding domain and show significant homology in their carboxylterminal activation domains. Expression of FBP is detected in undifferentiated cells and is substantially decreased following cellular differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FUBP3