Frizzled-4 Antibody (3G7)

Western Blot: Frizzled-4 Antibody (3G7) [H00008322-M02] - Analysis of FZD4 expression in transfected 293T cell line by FZD4 monoclonal antibody (M02), clone 3G7.Lane 1: FZD4 transfected lysate (Predicted MW: 59.9 KDa).Lane 2: Non-transfected lysate.

Sandwich ELISA: Frizzled-4 Antibody (3G7) [H00008322-M02] - Detection limit for recombinant GST tagged FZD4 is 0.1 ng/ml as a capture antibody.

Product Discontinued

Frizzled-4 Antibody (3G7) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: FZD4 (NP_036325, 107 a.a. ~ 206 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. TEKINIPIGPCGGMCLSVKRRCEPVLKEFGFAWPESLNCSKFPPQNDHNHMCMEGPGDEEVPLPHKTPIQPGEECHSVGTNSDQYIWVKRSLNCVLKCGY
• Specificity: FZD4 - frizzled homolog 4 (Drosophila) (3G7)
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: FZD4
• Purity: Ascites

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Ascites

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Frizzled-4 Antibody (3G7)

• CD344 antigen
• CD344
• EVR1
• exudative vitreoretinopathy 1
• FEVR
• frizzled (Drosophila) homolog 4
• frizzled homolog 4 (Drosophila)
• Frizzled4
• Frizzled-4
• Fz-4
• FZD4
• FZD4S
• FzE4
• GPCR
• hFz4
• MGC34390
• WNT receptor frizzled-4

Background

This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FZD4