Frataxin Antibody (OTI1C12) [DyLight 405]

• Reactivity: Hu
• Applications: WB, Flow, ICC/IF, IHC
• Clone: OTI1C12
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 405

Frataxin Antibody (OTI1C12) [DyLight 405] Summary

• Immunogen: Full length recombinant protein of human Frataxin (NP_000135) produced in HEK293T cells.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: FXN
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Frataxin Antibody (OTI1C12) [DyLight 405]

• CyaY
• EC 1.16.3.1
• FA
• FARRmitochondrial
• frataxin
• Friedreich ataxia protein
• Friedreich ataxia
• Fxn
• X25MGC57199

Background

Frataxin encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FXN