FoxO1/FKHR Antibody

Product Discontinued

FoxO1/FKHR Antibody Summary

• Immunogen: Peptide with sequence QDNKSSYGGMSQYNC corresponding to internal region according to NP_002006.2.
• Epitope: QDNKSSYGGMSQYNC
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: FOXO1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:128000
  • Western Blot 1 - 3 ug/ml
• Application Notes: WB: Approx. 60-65 kDa band observed in human umbilical cord lysates (calculated MW of 69.7 kDa band according to NP_002006.2).
• Control:

  FoxO1/FKHR Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris (pH 7.3), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for FoxO1/FKHR Antibody

• FKH1
• FKHR
• FKHRforkhead box protein O1
• forkhead box O1
• Forkhead box protein O1A
• forkhead homolog in rhabdomyosarcoma
• Forkhead in rhabdomyosarcoma
• FoxO1
• FOXO1Aforkhead, Drosophila, homolog of, in rhabdomyosarcoma

Background

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for FoxO1/FKHR Antibody (NB100-59744)(1)

Publication using NB100-59744

• Paik JH, Kollipara R, Chu G et al. FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Cell 2007-01-26 [PMID: 17254969]

Bioinformatics

• Gene Symbol: FOXO1
• Entrez:
  • 2308(Human)
• Uniprot:
  • NP_002006.2(Human)