FFAR3/GPR41 Antibody (2590G) [Alexa Fluor™ Plus 647]

• Reactivity: Hu
• Clone: 2590G
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Alexa Fluor Plus 647

FFAR3/GPR41 Antibody (2590G) [Alexa Fluor™ Plus 647] Summary

• Specificity: Detects human FFAR3 in direct ELISAs.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FFAR3/GPR41 Antibody (2590G) [Alexa Fluor™ Plus 647]

• FFA3
• FFA3R
• FFAR3
• free fatty acid receptor 3
• G protein-coupled receptor 41
• GPR41
• GPR41FFA3R
• G-protein coupled receptor 41

Background

GPR41 and GPR42 are two closely related genes that are part of a cluster of four adjacent G protein-coupled receptors(GPR40, 41, 42, and 43). There are only six nucleotide and amino acid differences between GPR41 and GPR42. GPR41 is a receptor for short chain fatty acids. The rank order of potency for agonists of this receptor ispropionate = pentanoate= butyrate > acetate > formate. The activity of this receptor is coupled to the formation of inositol 1,4,5-trisphosphate, intracellular Ca2+ mobilization, the activation of ERK 1/2 and inhibition of intracellular cAMP accumulation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.