FCAR/CD89 Antibody (MIP8a) [Janelia Fluor® 549]

• Reactivity: Hu
• Applications: WB, ELISA, Flow, IP
• Clone: MIP8a
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 549

FCAR/CD89 Antibody (MIP8a) [Janelia Fluor® 549] Summary

• Immunogen: Recombinant soluble human Fc alpha R
• Localization: Type I membrane protein (isoforms A); secreted (isoforms B).
• Specificity: NB100-63266 recognizes the human CD89 cell surface antigen, a 50-75kD cell surface glycoprotein that is also known as the IgA receptor (Fc alpha R). CD89 is expressed by peripheral blood monocytes and neutrophils. Clone MIP8a blocks binding of IgA to the Fc alpha R, and also inhibits neutrophil phagocytosis of IgA complexes.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: FCAR
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for FCAR/CD89 Antibody (MIP8a) [Janelia Fluor® 549]

• CD89 antigen
• CD89
• CD89IgA Fc receptor
• Fc alpha receptor
• Fc fragment of IgA, receptor for
• FCAR
• immunoglobulin alpha Fc receptor

Background

The CD89 gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. Thereceptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils,monocytes, macrophages, and eosin

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FCAR