FANCI Antibody

Western Blot: FANCI Antibody [NB300-244] - Nuclear extract (5 and 20 ug) from HeLa cells. Antibody used at 0.2 ug/ml.

Product Discontinued

FANCI Antibody Summary

• Immunogen: A synthetic peptide mapping to a region between residues 450 and 500 of human KIAA1794/FLJ10719 using the numbering given in TrEMBL entry Q9NVI1 (GeneID 55215).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: FANCI
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:2500-1:10000
• Application Notes: This antibody can be used for Western Blot. Immunoprecipitation and immunohistochemistry have not been tested. Suggested working dilutions: * Western Blot 1:2,500-1:10,000 *The investigator should determine the optimal working dilution for a specific application.
• Control:

  HeLa Nuclear Cell Lysate

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for FANCI Antibody

• Fanconi anemia group I protein
• Fanconi anemia, complementation group I
• KIAA1794FLJ10719
• Protein FACI

Background

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FANCI
• Entrez:
  • 55215(Human)
• Uniprot:
  • Q9NVI1(Human)