Factor IX Antibody (003) - Azide and BSA Free

• Reactivity: Mu
• Applications: ELISA
• Clone: 003
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Factor IX Antibody (003) - Azide and BSA Free Summary

• Description: This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Factor IX (Uniprot#: P16294; Met1-Thr471).
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: F9
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:5000-1:10000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 um filtered solution in PBS
• Preservative: No Preservative
• Purity: Protein A purified

Alternate Names for Factor IX Antibody (003) - Azide and BSA Free

• Christmas Factor
• Coagulation Factor IX
• EC 3.4.21
• EC 3.4.21.22
• F9
• factor 9
• FIX
• HEMB
• MGC129641
• MGC129642
• P19
• Plasma Thromboplastic Component
• Plasma thromboplastin component
• PTC
• THPH8

Background

Factor IX encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Factor IX Antibody (NBP2-90548)(1)

Publication using NBP2-90548

• Cohen H, Keren-Politansky A, Crispel Y et al. Calcium Prevents Enhanced Degradation of Factor VIII in the Condition of Motion Biology 2023-10-30 [PMID: 37997987]

Bioinformatics

• Gene Symbol: F9