Exostosin 1 Antibody - Azide and BSA Free

Western Blot: Exostosin 1 Antibody [H00002131-D01P] - Analysis of EXT1 expression in human liver.

Immunocytochemistry/Immunofluorescence: Exostosin 1 Antibody [H00002131-D01P] - Analysis of antibody to EXT1 on HeLa cell. Antibody concentration 10 ug/ml.

Western Blot: Exostosin 1 Antibody [H00002131-D01P] - Analysis of EXT1 expression in transfected 293T cell line by EXT1 polyclonal antibody.Lane 1: EXT1 transfected lysate(86.30 KDa).Lane 2: Non-transfected lysate.

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Exostosin 1 Antibody - Azide and BSA Free Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: EXT1 (NP_000118.2, 1 a.a. - 746 a.a.) full-length human protein. MQAKKRYFILLSAGSCLALLFYFGGLQFRASRSHSRREEHSGRNGLHHPSPDHFWPRFPDALRPFVPWDQLENEDSSVHISPRQKRDANSSIYKGKKCRMESCFDFTLCKKNGFKVYVYPQQKGEKIAESYQNILAAIEGSRFYTSDPSQACLFVLSLDTLDRDQLSPQYVHNLRSKVQSLHLWNNGRNHLIFNLYSGTWPDYTEDVGFDIGQAMLAKASISTENFRPNFDVSIPLFSKDHPRTGGERGFLKFNTIPPLRKYMLVFKGKRYLTGIGSDTRNALYHVHNGEDVVLLTTCKHGKDWQKHKDSRCDRDNTEYEKYDYREMLHNATFCLVPRGRRLGSFRFLEALQAACVPVMLSNGWELPFSEVINWNQAAVIGDERLLLQIPSTIRSIHQDKILALRQQTQFLWEAYFSSVEKIVLTTLEIIQDRIFKHISRNSLIWNKHPGGLFVLPQYSSYLGDFPYYYANLGLKPPSKFTAVIHAVTPLVSQSQPVLKLLVAAAKSQYCAQIIVLWNCDKPLPAKHRWPATAVPVVVIEGESKVMSSRFLPYDNIITDAVLSLDEDTVLSTTEVDFAFTVWQSFPERIVGYPARSHFWDNSKERWGYTSKWTNDYSMVLTGAAIYHKYYHYLYSHYLPASLKNMVDQLANCEDILMNFLVSAVTKLPPIKVTQKKQYKETMMGQTSRASRWADPDHFAQRQSCMNTFASWFGYMPLIHSQMRLDPVLFKDQVSILRKKYRDIERL
• Specificity: EXT1 - exostoses (multiple) 1,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: EXT1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Exostosin 1 Antibody - Azide and BSA Free

• EC 2.4.1.224
• EC 2.4.1.225
• exostoses (multiple) 1
• Exostosin 1
• exostosin-1
• EXT
• EXT1
• Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
• Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan4-alpha-N-acetylglucosaminyltransferase
• Langer-Giedion syndrome chromosome region
• LGCR
• LGS
• Multiple exostoses protein 1
• N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase
• Putative tumor suppressor protein EXT1
• TRPS2
• TTV

Background

This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Exostosin 1 Antibody (H00002131-D01P)(1)

Publication using H00002131-D01P

• Tian Chen, Yan Rengna, Wen Shuzhen et al. A splice mutation and mRNA decay of EXT2 provoke hereditary multiple exostoses. PLoS One. 2014-04-11 [PMID: 24728384] (WB)

Bioinformatics

• Gene Symbol: EXT1
• Entrez:
  • 2131(Human)
• Uniprot:
  • NP_000118.2(Human)