EVI2B Antibody (MEM-216) [CoraFluor™ 1]

• Reactivity: Hu
• Applications: Flow, IP
• Clone: MEM-216
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: CoraFluor 1

EVI2B Antibody (MEM-216) [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
• Additional Information: Clone MEM-216 was used by HLDA to establish CD designation.
• Immunogen: Raji cells
• Specificity: The antibody BP53-12 recognizes defined epitope (aa 16-25) on human p53, a 50 kDa tumour suppressor found in increased amounts in a wide variety of transformed cells; it is frequently mutated or inactivated in many types of cancer.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: EVI2B
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunoprecipitation
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for EVI2B Antibody (MEM-216) [CoraFluor™ 1]

• CD361 antigen
• D17S376
• Ecotropic viral integration site 2B protein homolog
• ecotropic viral integration site 2B
• EVDBprotein EVI2B
• EVI-2B

Background

The EVI2B gene encodes a 448 amino acid long, 48 kDA EVI2B protein that is frequently researched regarding its role in neurofibromatosis, leukemia, and myeloid leukemia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EVI2B