ETFA Antibody (OTI5C4) [Allophycocyanin]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: OTI5C4
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin

ETFA Antibody (OTI5C4) [Allophycocyanin] Summary

• Immunogen: Full length human recombinant protein of human ETFA (NP_000117) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ETFA
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for ETFA Antibody (OTI5C4) [Allophycocyanin]

• alpha-ETF
• electron transfer flavoprotein alpha-subunit
• Electron transfer flavoprotein subunit alpha, mitochondrial
• electron-transfer-flavoprotein, alpha polypeptide
• EMA
• GA2
• glutaric aciduria II
• MADD

Background

ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ETFA