ERCC8 Antibody [mFluor Violet 450 SE]

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: mFluor Violet 450 SE

ERCC8 Antibody [mFluor Violet 450 SE] Summary

• Immunogen: Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the human ERCC8.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ERCC8
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for ERCC8 Antibody [mFluor Violet 450 SE]

• CKN1DNA excision repair protein ERCC-8
• Cockayne syndrome 1 (classical)
• Cockayne syndrome WD repeat protein CSA
• CSACockayne syndrome WD-repeat protein CSA
• excision repair cross-complementing rodent repair deficiency, complementationgroup 8

Background

ERCC8 encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ERCC8