ERCC8 Antibody

Images

 
Western Blot: ERCC8 Antibody [NBP1-32166] - A. Neuro2A whole cell lysate/extract. B. GL261 whole cell lysate/extract. C. C8D30 whole cell lysate/extract. D. NIH-3T3 whole cell lysate/extract. E. Raw264.7 whole cell ...read more
Immunocytochemistry/ Immunofluorescence: ERCC8 Antibody [NBP1-32166] - Paraformaldehyde-fixed A431, using antibody at 1:200 dilution.
Western Blot: ERCC8 Antibody [NBP1-32166] - Sample (30 ug of whole cell lysate) NIH-3T3 10% SDS PAGE; antibody diluted at 1:1000.
Western Blot: ERCC8 Antibody [NBP1-32166] - Sample(30 ug of whole cell lysate) A:293T B:A431 12% SDS PAGE, antibody diluted at 1:500.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, Func, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

ERCC8 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human ERCC8. The exact sequence is proprietary.
Localization
Nucleus
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ERCC8
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Functional
  • Immunocytochemistry/Immunofluorescence 1:100-1:1000

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0) and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ERCC8 Antibody

  • CKN1DNA excision repair protein ERCC-8
  • Cockayne syndrome 1 (classical)
  • Cockayne syndrome WD repeat protein CSA
  • CSACockayne syndrome WD-repeat protein CSA
  • excision repair cross-complementing rodent repair deficiency, complementationgroup 8

Background

This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for ERCC8 Antibody (NBP1-32166) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for ERCC8 Antibody (NBP1-32166)

Discover related pathways, diseases and genes to ERCC8 Antibody (NBP1-32166). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on ERCC8.

NER Antibodies in Cancer Research
We at Novus Biologicals have over 230 products in our antibody catalog devoted to nucleotide excision repair. NER is a multi-stage sequential process involving over 30 proteins, all of which have been widely studied. Being the primary method to repair...  Read full blog post.

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Bioinformatics

Gene Symbol ERCC8