ERCC8 Antibody

Western Blot: ERCC8 Antibody [H00001161-D01P] - Analysis of ERCC8 expression in transfected 293T cell line by ERCC8 polyclonal antibody.Lane 1: ERCC8 transfected lysate(44.10 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

ERCC8 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: ERCC8 (NP_000073.1, 1 a.a. - 396 a.a.) full-length human protein. MLGFLSARQTGLEDPLRLRRAESTRRVLGLELNKDRDVERIHGGGINTLDIEPVEGRYMLSGGSDGVIVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNYGKVCNNSKKGLKFTVSCGCSSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRDCNILAWVPSLYEPVPDDDETTTKSQLNPAFEDAWSSSDEEG
• Specificity: ERCC8 - excision repair cross-complementing rodent repair deficiency, complementation group 8,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ERCC8
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ERCC8 Antibody

• CKN1DNA excision repair protein ERCC-8
• Cockayne syndrome 1 (classical)
• Cockayne syndrome WD repeat protein CSA
• CSACockayne syndrome WD-repeat protein CSA
• excision repair cross-complementing rodent repair deficiency, complementationgroup 8

Background

This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ERCC8
• Entrez:
  • 1161(Human)
• Uniprot:
  • NP_000073.1(Human)