Equine IL-1ra/IL-1F3 DuoSet ELISA, 15 Plate

• Reactivity: Eq
• Applications: ELISA
• Conjugate: Biotin

Equine IL-1ra/IL-1F3 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Equine IL-1ra/IL-1F3 DuoSet ELISA, 15 Plate

• DIRA
• ICIL-1ra
• IL1F3
• IL-1F3
• IL1ra
• IL-1ra
• IL-1ra3
• IL1RN
• IL-1RN
• interleukin 1 receptor antagonist
• IRAP
• MVCD4

Background

IL-1ra (IL-1 receptor antagonist) is a widely expressed acute phase protein that serves to dampen inflammation. IL-1ra binds to both IL-1 RI and IL-1 RII. It competitively inhibits IL-1 (alpha or beta) binding to IL-1 RI and does not trigger recruitment of the accessory molecule IL-1 R AcP or activation of IL-1 RI signaling. IL-1ra blocks the proinflammatory actions of IL-1 including Prostaglandin E2 and IL-6 release from endothelial cells, fever generation, thrombocytosis, the production of hepatic acute phase proteins, and neutrophil expansion and infiltration.

Publications for IL-1ra/IL-1F3/IL1RN (DY2466)(5)

Publications using DY2466

• Fukuda, K;Mita, H;Tamura, N;Kuroda, T;Kuwano, A;Takahashi, T;Sato, F; Characteristic inflammatory biomarkers in an equine model of persistent synovitis induced by the intra-articular administration of monoiodoacetic acid Journal of equine veterinary science 2023-05-18 [PMID: 37209789] (Equine)
• RF Jiménez-Ar, C López, ME Álvarez, C Giraldo, M Prades, JU Carmona Long-term cytokine and growth factor release from equine platelet-rich fibrin clots obtained with two different centrifugation protocols Cytokine, 2017-06-23;97(0):149-155. 2017-06-23 [PMID: 28648869] (Equine)
• Simon Rütten Release kinetics of tumor necrosis factor-? and interleukin-1 receptor antagonist in the equine whole blood BMC Vet Res, 2016-06-17;12(1):117. 2016-06-17 [PMID: 27316332] (Equine)
• Goodrich L, Grieger J, Phillips J, Khan N, Gray S, McIlwraith C, Samulski R scAAVIL-1ra dosing trial in a large animal model and validation of long-term expression with repeat administration for osteoarthritis therapy. Gene Ther, 2015-04-23;22(7):536-45. 2015-04-23 [PMID: 25902762] (Equine)
• Ishihara A, Bartlett JS, Bertone AL Inflammation and immune response of intra-articular serotype 2 adeno-associated virus or adenovirus vectors in a large animal model. Arthritis, 2012-01-11;2012(0):735472. 2012-01-11 [PMID: 22288012] (Equine)

FAQs for IL-1ra/IL-1F3/IL1RN (DY2466). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.