ENOX2 Antibody

Product Discontinued

ENOX2 Antibody Summary

• Immunogen: Peptide with sequence C-EKLKDDKLQVEK, from the internal region of the protein sequence according to NP_006366.2; NP_872114.1.
• Specificity: This antibody is expected to recognise both reported isoforms (NP_006366.2; NP_872114.1).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ENOX2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 2-4ug/ml
  • Immunohistochemistry-Paraffin 2-4ug/ml
  • Peptide ELISA Detection limit 1:64000
• Application Notes: In paraffin embedded Human Kidney shows cytoplasm staining preferentially in PC.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Canine.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris (pH 7.3), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for ENOX2 Antibody

• COVA1
• Cytosolic ovarian carcinoma antigen 1APK1 antigen
• ecto-NOX disulfide-thiol exchanger 2
• tNOXAPK1
• Tumor-associated hydroquinone oxidase

Background

The protein encoded by the ENOX2 gene is a growth-related cell surface protein. It was identifed because it reacts with the monoclonal antibody KI in cells, such as the ovarian carcinoma line OVCAR-3, also expressing the CAKI surface glycoprotein. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The two activities alternate with a period length of about 24 minutes. The encoded protein also displays prion-like properties. Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ENOX2
• Entrez:
  • 10495(Human)
• Uniprot:
  • NP_006366.2(Human)