ELL Antibody (24GB8330)

• Reactivity: Hu, Mu, Rt
• Applications: WB, Flow
• Clone: 24GB8330
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

ELL Antibody (24GB8330) Summary

• Description: Reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.
• Immunogen: Recombinant protein of human ELL (Uniprot: P55199)
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ELL
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for ELL Antibody (24GB8330)

• C19orf17
• chromosome 19 open reading frame 17
• DKFZp434I1916
• Eleven-nineteen lysine-rich leukemia protein
• ELL gene (11-19 lysine-rich leukemia gene)
• ELL1
• elongation factor RNA polymerase II
• MEN
• RNA polymerase II elongation factor ELL

Background

Eleven-nineteen lysine-rich leukemia protein (ELL) was originally identified in a screen for genes that fuse to MLL (myeloid-lymphoid leukemia) in the t(11;19)(q23;p13.1) breakpoint. ELL is an elongation factor that increases the catalytic rate of RNA pol II by suppressing transient pausing of RNA pol II. ELL has been shown to be essential to development and important to cell growth and survival. Alternate names for ELL include RNA polymerase II elongation factor ELL, ELL1, and men.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ELL