EIF3A Antibody

Product Discontinued

EIF3A Antibody Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: EIF3S10 (NP_003741, 1 a.a. - 75 a.a.) partial recombinant protein with GST tag. MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHRTWQKIHEPIMLKYLELCVDLRKSHLAKEGLYQYK
• Specificity: EIF3S10
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: EIF3A
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: It has been used for ELISA and WB.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Whole antisera with 50% Glycerol
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for EIF3A Antibody

• centrosomin homolog
• cytoplasmic protein p167
• eIF3 p167
• eIF3 p180
• eIF3 p185
• EIF3, p180 subunit
• eIF3a
• eIF3-p170
• EIF3S10EIF3
• eIF-3-theta
• eIF3-theta
• Eukaryotic translation initiation factor 3 subunit 10
• eukaryotic translation initiation factor 3 subunit A
• eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD)
• eukaryotic translation initiation factor 3, subunit 10 (theta, 170kD)
• eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa
• eukaryotic translation initiation factor 3, subunit 10, 170kD
• eukaryotic translation initiation factor 3, subunit A
• KIAA0139P167
• p180
• p185
• TIF32

Background

Eukaryotic initiation factor 3 subunit A (eIF3A) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5'-end of cellular mRNAs near the cap structure (m7GpppN). eIF3A is also known as EIF3S10 (eukaryotic initiation factor 3 subunit 7). eIF3A is the largest subunit of the eIF3 complex. eIF3A expression is regulated through the cell cycle. It's expression peaks in S-phase and it is proposed to play a role in regulating the translation of mRNAs involved in the regulation of cell cycle progression and proliferation. Alternative names for eIF3A include eIF-3-theta, eIF-3 p167, eIF-3 p170, eIF-3 p180, eIF3-p185, EIF3S10, and KIAA0139.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for EIF3A Antibody (H00008661-A01)(1)

Publication using H00008661-A01

• Kroczynska B, Kaur S, Katsoulidis E, et, al. Interferon-dependent engagement of eukaryotic initiation factor 4B (eIF4B) via S6K- RSK-mediated signals . Mol Cell Biol. 2009-03-16 [PMID: 19289497]

Bioinformatics

• Gene Symbol: EIF3A
• Entrez:
  • 8661(Human)
• OMIM:
  • 602039(Human)
• Uniprot:
  • NP_003741(Human)