EDNRA/Endothelin R Type A Antibody (RB19282)

Product Discontinued

EDNRA/Endothelin R Type A Antibody (RB19282) Summary

• Immunogen: This EDNRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-154 amino acids from the Central region of human EDNRA.
• Localization: Cellular Location Cell membrane; Multi-pass membrane protein. Tissue Location Isoform 1, isoform 3 and isoform 4 are expressed in a variety of tissues, with highest levels in the aorta and cerebellum, followed by lung, atrium and cerebral cortex, lower levels in the placenta, kidney, adrenal gland, duodenum, colon, ventricle and liver but no expression in umbilical vein endothelial cells. Within the placenta, isoform 1, isoform 2, isoform 3 and isoform 4 are expressed in the villi and stem villi vessels
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: EDNRA
• Purity: Ammonium sulfate precipitation

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:10 - 1:50
  • Immunocytochemistry/ Immunofluorescence 1:10 - 1:50
  • Western Blot 1:1000
• Theoretical MW: 48.722 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Predicted to react with Mouse and Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 2 mg/ml
• Purity: Ammonium sulfate precipitation

Alternate Names for EDNRA/Endothelin R Type A Antibody (RB19282)

• EDNRA
• endothelin receptor type A
• endothelin-1 receptor
• endothelin-1-specific receptor
• ET1-specific type
• ETAR
• ETRA
• G protein-coupled receptor
• hET-AR

Background

EDNRA is a receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EDNRA
• Uniprot:
  • P25101(Human)