EDA2R/TNFRSF27/XEDAR Antibody (072) [Alexa Fluor™ Plus 680]

• Reactivity: Hu
• Applications: ELISA
• Clone: 072
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Alexa Fluor Plus 680

EDA2R/TNFRSF27/XEDAR Antibody (072) [Alexa Fluor™ Plus 680] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: This antibody was obtained from a rabbit immunized with purified, recombinant Human EDA2R/TNFRSF27/XEDAR (Accession#: NP_068555.1; Met1-Thr138).
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: EDA2R
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for EDA2R/TNFRSF27/XEDAR Antibody (072) [Alexa Fluor™ Plus 680]

• ectodysplasin A2 receptor
• EDA2R
• EDA-A2 receptor
• EDAA2R
• EDA-A2R
• EDAA2Rtumor necrosis factor receptor superfamily member XEDAR
• EDAR2
• TNFRSF27
• XEDAR
• XEDARTNFRSF27tumor necrosis factor receptor superfamily member 27
• X-linked ectodysplasin-A2 receptor

Background

EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EDA2R