DYRK2 Antibody Blocking Peptide

• Reactivity: Hu
• Applications: AC
• Concentration: 0.2 mg/ml

DYRK2 Antibody Blocking Peptide Summary

• Description: A blocking peptide containing 18 amino acids near the carboxy terminus of human DYRK2.

  Source: Synthetic

  (Accession #: NP_006473)

• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: DYRK2
• Purity: N/A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NBP1-76560.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
• Preservative: 0.02% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: N/A

Alternate Names for DYRK2 Antibody Blocking Peptide

• dual specificity tyrosine-phosphorylation-regulated kinase 2
• dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
• DYRK2
• EC 2.7.12
• EC 2.7.12.1
• FLJ21217
• FLJ21365

Background

DYRK2, or dual specificity tyrosine-phosphorylation-regulated kinase 2, has a role in the regulation of cellular growth and/or development. In response to DNA damage, DYRK2 regulates p53 phosphorylation on Ser-46 to induce apoptosis. DYRK2 has been proposed to inactivate GYS1 by phosphorylation at Ser-641, and potentially a second phosphorylation site, thus regulating glycogen synthesis. DYRK2 also phosphorylates EIF2B5 at Ser-544, enabling its subsequent phosphorylation and inhibition by GSK3, and may play a more general role in the priming of GSK3 substrates.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: DYRK2