DYRK2 Products

Antibodies
DYRK2 Antibody
DYRK2 Antibody
NBP1-89516
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
DYRK2 Antibody (599542) [Unco ...
DYRK2 Antibody (599542) [Unconjuga...
MAB5408
Species: Hu, Rt
Applications: WB, IHC
Host: Mouse Monoclonal
DYRK2 Antibody
DYRK2 Antibody
AF5408
Species: Hu, Mu, Rt
Applications: WB
Host: Sheep Polyclonal
Proteins
Recombinant Human DYRK2 Prote ...
Recombinant Human DYRK2 Protein
H00008445-P01
Species: Hu
Applications: WB, ELISA, PA, PAGE, KA
DYRK2 Recombinant Protein Ant ...
DYRK2 Recombinant Protein Antigen
NBP2-58747PEP
Species: Hu
Applications: B/N, Ctrl
DYRK2 Recombinant Protein Ant ...
DYRK2 Recombinant Protein Antigen
NBP1-89516PEP
Species: Hu
Applications: AC
RNAi
DYRK2 RNAi
DYRK2 RNAi
H00008445-R06
Species: Hu
Applications: RNAi, RNAi SP
DYRK2 RNAi
DYRK2 RNAi
H00008445-R05
Species: Hu
Applications: RNAi, RNAi SP

Description

DYRK2, or dual specificity tyrosine-phosphorylation-regulated kinase 2, has a role in the regulation of cellular growth and/or development. In response to DNA damage, DYRK2 regulates p53 phosphorylation on Ser-46 to induce apoptosis. DYRK2 has been proposed to inactivate GYS1 by phosphorylation at Ser-641, and potentially a second phosphorylation site, thus regulating glycogen synthesis. DYRK2 also phosphorylates EIF2B5 at Ser-544, enabling its subsequent phosphorylation and inhibition by GSK3, and may play a more general role in the priming of GSK3 substrates.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 8445
Alternate Names
  • EC 2.7.12
  • dual specificity tyrosine-phosphorylation-regulated kinase 2
  • FLJ21365
  • FLJ21217
  • EC 2.7.12.1
  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2

Research Areas for DYRK2

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Protein Kinase

PTMs for DYRK2

Learn more about PTMs related to DYRK2.

Phosphorylation
Acetylation
Methylation
Dephosphorylation
Ubiquitination

Bioinformatics Tool for DYRK2

Discover related pathways, diseases and genes to DYRK2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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