Dopamine D3R/DRD3 Antibody - BSA Free

Immunohistochemistry-Paraffin: Dopamine D3R/DRD3 Antibody [NBP1-02398] - Staining of human brain, cortex tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.

Product Discontinued

Dopamine D3R/DRD3 Antibody - BSA Free Summary

• Immunogen: Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human Dopamine D3R/DRD3.
• Epitope: 3rd cytoplasmic domain
• Specificity: Human Dopamine D3R/DRD3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Mouse (94%), Bovine (94%), Rabbit (94%), Canine (94%), Hamster (94%), Bat (94%), Equine (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DRD3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 20 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Chimpanzee (100%), Gorilla (100%), Marmoset (100%), Gibbon (94%), Elephant (94%), Panda (94%), Rat (88%), Porcine (88%), Opossum (88%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Dopamine D3R/DRD3 Antibody - BSA Free

• D(3) dopamine receptor
• D3DR
• Dopamine D3 R
• Dopamine D3 receptor
• Dopamine D3R
• dopamine receptor D3
• DRD3
• essential tremor 1
• ETM1
• FET1
• MGC149204
• MGC149205

Background

The DRD3 Dopamine Receptor is expressed in brain regions associated with cognitive, emotional, and endocrine functions. DRD3 mediates the effects of drugs used in the treatment of schizophrenia and Parkinson's disease. DRD3 also binds BP897, a potent inhibitor of drug-craving and cocaine-seeking behaviors. Mutations in DRD3 lead to sodium retention in the kidney, resulting in hypertension and increased locomotor activity in mice. Multiple isoforms of DRD3 are produced by alternative splicing.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DRD3
• Entrez:
  • 1814(Human)
• Uniprot:
  • P35462()