Dopamine beta-Hydroxylase Antibody (DBH/7222) [Alexa Fluor™ Plus 680]

• Reactivity: Hu
• Applications: IHC
• Clone: DBH/7222
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 680

Dopamine beta-Hydroxylase Antibody (DBH/7222) [Alexa Fluor™ Plus 680] Summary

• Immunogen: Recombinant fragment (around aa200-400) of human Dopamine beta-Hydroxylase protein (exact sequence is proprietary)
• Localization: Cytoplasm
• Isotype: IgG2 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: DBH
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Dopamine beta-Hydroxylase Antibody (DBH/7222) [Alexa Fluor™ Plus 680]

• DBH
• DBM
• dopamine beta-hydroxylase (dopamine beta-monooxygenase)
• Dopamine betaHydroxylase
• Dopamine beta-Hydroxylase
• Dopamine beta-monooxygenase
• DOPBHY
• EC 1.14.17.1

Background

Dopamine beta-hydroxylase belongs to the copper type II, ascorbate-dependent monooxygenase family and catalyzes the oxidative hydroxylation of dopamine to noradrenaline. It is almost exclusively located in the adrenal medulla and the synaptic vesicles of postganglionic sympathetic neurons being expressed in noradrenergic and adrenergic neurons. DBH serves as a marker of noradrenergic cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DBH