DMC1 Antibody (4A10)

Images

 
Western Blot: DMC1 Antibody (4A10) [H00011144-M10] - Analysis of DMC1 expression in PC-12 (Cat # L012V1).
Immunocytochemistry/ Immunofluorescence: DMC1 Antibody (4A10) [H00011144-M10] - Analysis of monoclonal antibody to DMC1 on HeLa cell. Antibody concentration 10 ug/ml
Western Blot: DMC1 Antibody (4A10) [H00011144-M10] - Analysis of DMC1 expression in Hela S3 NE (Cat # L013V3).
Sandwich ELISA: DMC1 Antibody (4A10) [H00011144-M10] - Detection limit for recombinant GST tagged DMC1 is 0.3 ng/ml as a capture antibody.

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF
Clone
4A10
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

DMC1 Antibody (4A10) Summary

Immunogen
DMC1 (NP_008999, 237 a.a. ~ 340 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.GELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAK
Specificity
Reacts with DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast).
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
DMC1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunocytochemistry/Immunofluorescence
Application Notes
This antibody is reactive against cell lysate in western blot and recombinant protein in ELISA.

Reactivity Notes

Human, Rat.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for DMC1 Antibody (4A10)

  • disrupted meiotic cDNA1, yeast, homolog of
  • DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologousrecombination (yeast)
  • DMC1 homologue
  • HsLim15
  • LIM15yeast homolog) meiosis-specific homologousrecombination
  • meiotic recombination protein DMC1/LIM15 homolog
  • MGC150472
  • MGC150473

Background

The protein encoded by this gene is essential for meiotic homologous recombination. Genetic recombination in meiosis plays an important role in generating diversity of genetic information. The product of this gene is structurally and evolutionary related to the products of the yeast RAD51 and E. coli RecA genes. Alternative splice variants of this gene have been described but their full-length nature has not been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for DMC1 Antibody (H00011144-M10)

Discover related pathways, diseases and genes to DMC1 Antibody (H00011144-M10). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on DMC1.

Determining DMC1's role in Homologus Recombination
The DMC1 gene encodes a 36.7 kDa nuclear protein involved in meiotic homologous recombination. This recombinase is functionally related to the yeast RAD51 and E. coli RecA genes. In contrast to RAD51, which functions in both mitotic and meiotic recomb...  Read full blog post.

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Bioinformatics

Gene Symbol DMC1
Entrez
Uniprot