DMC1 Antibody (2H12/4) [Janelia Fluor® 669]

Product Discontinued

DMC1 Antibody (2H12/4) [Janelia Fluor® 669] Summary

• Immunogen: Human DMC1 protein (expressed as 6xHis fusion in E. coli and band cut out of gel of insoluble pelet)
• Localization: Nuclear
• Specificity: Specific for DMC1 - does not cross-react with the related protein Rad51.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: DMC1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for DMC1 Antibody (2H12/4) [Janelia Fluor® 669]

• disrupted meiotic cDNA1, yeast, homolog of
• DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologousrecombination (yeast)
• DMC1 homologue
• HsLim15
• LIM15yeast homolog) meiosis-specific homologousrecombination
• meiotic recombination protein DMC1/LIM15 homolog
• MGC150472
• MGC150473

Background

DMC-1 is a meiosis-specific homologue of RecA/Rad51 and is an essential component of the meiotic recombination machinery in yeast and higher eukaryotes. DMC-1 is the human equivalent of e. coli recA.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DMC1