Dkk-4 Antibody [Janelia Fluor® 549]

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Janelia Fluor 549

Dkk-4 Antibody [Janelia Fluor® 549] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Dkk-4
  Leu19-Ile221 (Arg67Ser, Arg70Ser)
  Accession # Q8VEJ3
• Specificity: Detects mouse Dkk-4 in direct ELISAs and Western blots. In Western blots, less than 5% cross-reactivity with recombinant human Dkk-4, recombinant mouse (rm) Dkk-1, rmDkk-2, and rmDkk-3 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: DKK4
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Dkk-4 Antibody [Janelia Fluor® 549]

• dickkopf (Xenopus laevis) homolog 4
• dickkopf homolog 4 (Xenopus laevis)
• dickkopf-4
• dickkopf-related protein 4
• Dkk4
• Dkk-4
• hDkk-4
• MGC129562
• MGC129563

Background

DKK4 is a secreted protein that is a member of the dickkopf family. Like some other members of the dickkopf family DKK4 contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The activity of DKK4 is modulated by binding to the Wnt co-receptor and the co-factor kremen 2, and it is proposed that it is also an inhibitor of the Wnt signaling pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DKK4