DISP1 Antibody (768213) [Janelia Fluor® 525]

• Reactivity: Hu
• Applications: ICC/IF
• Clone: 768213
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 525

DISP1 Antibody (768213) [Janelia Fluor® 525] Summary

• Immunogen: E. coli-derived recombinant human DISP1
  Glu212-Lys492 and Ser746-Thr984
  Accession # Q96F81
• Specificity: Detects human DISP1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) DISP2 or rhSMAGP is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: DISP1
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for DISP1 Antibody (768213) [Janelia Fluor® 525]

• DISP1
• DISPA
• DISPAFLJ43740
• dispatched A
• dispatched homolog 1 (Drosophila)
• Dispatched
• DKFZp434I0428
• MGC104180
• MGC13130
• MGC16796
• protein dispatched homolog 1

Background

The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structuresoften depends upon the localized production of secreted protein signals. Cells surrounding the source of a particularsignal respond in a graded manner according to the effective concentration of the signal, and this response producesthe pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched hasbeen identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is oneof two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encodedprotein may play an essential role in Hh patterning activities in the early embryo. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DISP1