DISP1 Products

Description

The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo. [provided by RefSeq]

Bioinformatics

Product By Gene ID	84976
Alternate Names	DISP1 DISPA DISPAFLJ43740 dispatched A dispatched homolog 1 (Drosophila) Dispatched DKFZp434I0428 MGC104180 MGC13130 MGC16796 protein dispatched homolog 1

Research Areas for DISP1

Find related products by research area and learn more about each of the different research areas below.

Stem Cell Signaling Pathway