Defensin alpha 5 Antibody (972217) [Alexa Fluor® 700]

• Reactivity: Hu
• Applications: ELISA
• Clone: 972217
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 700

Defensin alpha 5 Antibody (972217) [Alexa Fluor® 700] Summary

• Immunogen: E. coli-derived recombinant human α-Defensin 5
  Thr64-Arg94
  Accession # Q01523
• Specificity: Detects human alpha -Defensin 5 in direct ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Defensin alpha 5 Antibody (972217) [Alexa Fluor® 700]

• alpha-Defensin 5
• DEF5
• DEF5defensin, alpha 5, preproprotein
• DEFA5
• defensin 5
• Defensin alpha 5
• Defensin, alpha 5
• defensin, alpha 5, Paneth cell-specific
• defensin-5
• HD-5
• MGC129728

Background

Defensin alpha 5 (DEFA5), also known as human alpha defensin 5 (HD5), is a secreted antimicrobial protein encoded by the DEFA5 gene and a member of the Defensins family. Defensins are thought to kill microbes by permeabilizing their plasma membrane. DEFA5 is expressed in Paneth cells, which are secretory epithelial cells in the small intestine. Unlike other defensins, DEFA5 is stored in secretory vesicles as a propeptide, and is processed into different peptides with different potency and localization.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.