DDX10 Antibody

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Independent Antibodies: Western Blot: DDX10 Antibody [NB100-1577] - Detection of Human DDX10 on HeLa whole cell lystate using NB100-1577. DDX10 was also immunoprecipitated with rabbit anti-DDX10 antibody ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml

Order Details

DDX10 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 825 and the C-terminus (residue 875) of human DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 10 using the numbering given in entry NP_004389.2 (GeneID 1662).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DDX10
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 1-4 ug/mg of lysate

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for DDX10 Antibody

  • DDX10-NUP98 fusion protein type 2
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
  • DEAD box protein 10
  • DEAD box-10
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 10 (RNA helicase)
  • EC 3.6.1
  • EC 3.6.4.13
  • HRH-J8
  • probable ATP-dependent RNA helicase DDX10

Background

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it may be involved in ribosome assembly. Fusion of this gene and the nucleoporin gene, NUP98, by inversion 11 (p15q22) chromosome translocation is found in the patients with de novo or therapy-related myeloid malignancies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol DDX10
Entrez
Uniprot