DDIT4L Antibody (DDIT-03) [Alexa Fluor™ Plus 594]

• Reactivity: Hu
• Applications: WB, Flow
• Clone: DDIT-03
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 594

DDIT4L Antibody (DDIT-03) [Alexa Fluor™ Plus 594] Summary

• Immunogen: N-terminal recombinant fragment of human DDIT4L (amino acids 2-98)
• Specificity: The antibody MEM-18 reacts with CD14, a 53-55 kDa GPI (glycosylphosphatidylinositol)-linked membrane glycoprotein expressed on monocytes, macrophages and weakly on granulocytes; also expressed by most tissue macrophages. In human, the epitope recognized by MEM-18 is located between amino acids 57-64.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: DDIT4L
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow (Intracellular)
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for DDIT4L Antibody (DDIT-03) [Alexa Fluor™ Plus 594]

• DNA damage-inducible transcript 4-like protein
• DNA-damage-inducible transcript 4-like
• HIF-1 responsive protein RTP801-like
• homolog of mouse SMHS1
• Protein regulated in development and DNA damage response 2
• REDD-2
• REDD2Rtp801L
• regulated in development and DNA damage response 2
• RTP801L

Background

DDIT4L, also known as DNA damage-inducible transcript 4-like protein, is a 21.7 kDa 193 amino acid protein that regulates the TOR signaling pathway between the TSC1-TSC2 complex and AKT1, thus inhibiting cell growth. Current research is being conducted with diseases and disorders such as teratoma, melanoma, and hypoxia. The protein is involved in the TOR signaling pathway, where it interacts with SNRPG and PRKAB2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DDIT4L