DBT Antibody (OTI1G2) [PE/Cy7]

Product Discontinued

DBT Antibody (OTI1G2) [PE/Cy7] Summary

• Immunogen: Full length recombinant protein of human DBT (NP_001909) produced in HEK293T cells.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: DBT
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
• Application Notes: Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for DBT Antibody (OTI1G2) [PE/Cy7]

• BCATE2BCKAD E2 subunit
• BCKADE2
• BCKAD-E2
• branched chain acyltransferase, E2 component
• Branched-chain alpha-keto acid dehydrogenase complex component E2
• Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto aciddehydrogenase complex
• dihydrolipoamide branched chain transacylase (E2 component of branched chainketo acid dehydrogenase complex; maple syrup urine disease)
• dihydrolipoamide branched chain transacylase E2
• Dihydrolipoamide branched chain transacylase
• dihydrolipoyl transacylase
• Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase
• E2 component of branched chain alpha-keto acid dehydrogenase complex
• E2
• E2B
• EC 2.3.1.168
• lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex, mitochondrial
• lipoamide acyltransferase component of mitochondrial branched-chain alpha-ketoacid dehydrogenase complex
• MGC9061
• mitochondrial branched chain alpha-keto acid dehydrogenase transacylase subunit(E2b)

Background

The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DBT