DARC Antibody (358307) [Allophycocyanin]

Images

 
Human red blood cells were stained with Mouse Anti-Human DARC APC-conjugated Monoclonal Antibody (Catalog # FAB4139A, filled histogram) or isotype control antibody (Catalog # IC003A, open histogram). View our ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
358307
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

DARC Antibody (358307) [Allophycocyanin] Summary

Immunogen
HEK293 human embryonic kidney cell line transfected with human DARC
Met1-Ser336
Accession # Q16570
Specificity
Detects human DARC. Stains human DARC transfected cells but not irrelevant transfectants.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
DARC
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Reviewed Applications
Read 1 Review rated 4
using
FAB4139A in the following application:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for DARC Antibody (358307) [Allophycocyanin]

  • ACKR1
  • CCBP1
  • CD234 antigen
  • CD234
  • DARC
  • Dfy
  • Duffy Antigen
  • Duffy antigen/chemokine receptor
  • Duffy blood group antigen
  • Duffy blood group, chemokine receptor
  • Fy Antigen
  • Fy glycoprotein
  • FYDuffy blood group
  • Glycoprotein D
  • GPD
  • GPDWBCQ1
  • GpFy
  • Plasmodium vivax receptor

Background

Duffy Antigen Receptor for Chemokines (DARC), also known as Fy glycoprotein and CD234, is a 7TM non-signaling chemokine receptor that is expressed on venular endothelial cells and erythrocytes. DARC binds and mediates the internalization of several inflammatory CC and CXC chemokines. It transports chemokines to the lumenal face of venular endothelium to promote the extravasation of leukocytes to sites of inflammation. DARC polymorphisms are important in blood transfusion compatibility and determine the susceptibility of erythrocytes to Plasmodium vivax infection. Human DARC shares 60% amino acid sequence identity with mouse DARC.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

MAB356
Species: Hu
Applications: WB, Flow, CyTOF-ready, ELISA(Cap), ELISA(Det), ELISA(Sta)
NBP2-07087
Species: Hu
NBP1-69668
Species: Hu
Applications: WB
NB500-525
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
MAB1228
Species: Hu
Applications: Flow, IHC, IP, CyTOF-ready
MAB208
Species: Hu
Applications: WB, CyTOF-ready, ELISA(Cap), ELISA(Det), ICC, ICFlow, Neut, ELISA(Sta)
NB300-221
Species: Hu, Mu, Rt, Po, Av, Bv, Ch, Eq, Fe, Ha, Op, Pm, Sh, Ze
Applications: WB, Simple Western, ChIP, ICC/IF, IHC, IP
NBP2-66881
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
AF3857
Species: Hu
Applications: WB
H00005236-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IP, RNAi
NBP1-88824
Species: Hu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-84597
Species: Hu
Applications: WB, IHC, IHC-P
FAB4139A
Species: Hu
Applications: Flow

Publications for DARC Antibody (FAB4139A) (0)

There are no publications for DARC Antibody (FAB4139A).
By submitting your publication information earn gift cards and discounts for future purchases.

Review for DARC Antibody (FAB4139A) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using FAB4139A:
Filter by Applications
Flow
(1)
All Applications
Filter by Species
Human
(1)
All Species
Images Ratings Applications Species Date Details
 
reviewed by:
Anonymous
Flow Human 01/26/2015
View

Summary

ApplicationFlow Cytometry
Sample TestedSee PMID: 20040767
SpeciesHuman

Blocking

Blocking DetailsSee PMID: 20040767

Details

Detection NotesSee PMID: 20040767

Comments

CommentsIndependent review from antibodyresource.comPublished in PMID: 20040767

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for DARC Antibody (FAB4139A) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Additional Array Products

Bioinformatics Tool for DARC Antibody (FAB4139A)

Discover related pathways, diseases and genes to DARC Antibody (FAB4139A). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for DARC Antibody (FAB4139A)

Discover more about diseases related to DARC Antibody (FAB4139A).
 

Pathways for DARC Antibody (FAB4139A)

View related products by pathway.

PTMs for DARC Antibody (FAB4139A)

Learn more about PTMs related to DARC Antibody (FAB4139A).

Blogs on DARC

There are no specific blogs for DARC, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Recent Reviews

4
5
0
4
1
3
0
2
0
1
0

 
Anonymous
01/26/2015
Application: Flow
Species: Human

Bioinformatics

Gene Symbol DARC
Uniprot