Cytohesin-1 Antibody

Western Blot: Cytohesin-1 Antibody [H00009267-D01P] - Analysis of CYTH1 expression in transfected 293T cell line by CYTH1 polyclonal antibody.Lane 1: PSCD1 transfected lysate(46.40 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

Cytohesin-1 Antibody Summary

• Immunogen: PSCD1 (NP_004753.1, 1 a.a. - 398 a.a.) full-length human protein. MEEDDSYVPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNNGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH
• Specificity: PSCD1 - pleckstrin homology, Sec7 and coiled-coil domains 1(cytohesin 1),
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CYTH1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500
• Application Notes: Antibody reactive against transfected lysate for western blot and recombinant protein with GST tag for ELISA and Western Blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Cytohesin-1 Antibody

• B2-1
• CYTH1
• cytoadhesin 1
• cytohesin 1
• Cytohesin1
• Cytohesin-1
• D17S811ECYTOHESIN-1
• FLJ34050
• FLJ41900
• homolog of secretory protein SEC7
• PH, SEC7 and coiled-coil domain-containing protein 1
• pleckstrin homology, Sec7 and coiled-coil domains 1
• PSCD1
• SEC7 homolog B2-1
• SEC7

Background

The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. The encoded protein is 83% homologous to that of CYTH2. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CYTH1
• Entrez:
  • 9267(Human)
• Uniprot:
  • NP_004753.1(Human)