Species: Hu
Applications: WB, ICC/IF, IHC, IP
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Host: Goat Polyclonal
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Description
Pleckstrin homology, Sec7 and coiled/coil domains 1 (PSCD1) is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The PSCD1 is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. PSCD1 protein is 83% homologous to PSCD2.
Bioinformatics
| Entrez |
Human
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
9267 |
| Alternate Names |
- B2-1
- cytoadhesin 1
- cytohesin 1
- cytohesin-1
- D17S811ECYTOHESIN-1
- FLJ34050
- FLJ41900
- homolog of secretory protein SEC7
- PH, SEC7 and coiled-coil domain-containing protein 1
- pleckstrin homology, Sec7 and coiled-coil domains 1
- PSCD1
- SEC7 homolog B2-1
- SEC7
|
