Cytohesin-1 Antibody [DyLight 550]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: DyLight 550

Cytohesin-1 Antibody [DyLight 550] Summary

• Immunogen: E. coli-derived recombinant human Cytohesin-1
  Met1-Tyr102
  Accession # Q15438
• Specificity: Detects endogenous human Cytohesin-1 in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: CYTH1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Cytohesin-1 Antibody [DyLight 550]

• B2-1
• CYTH1
• cytoadhesin 1
• cytohesin 1
• Cytohesin1
• Cytohesin-1
• D17S811ECYTOHESIN-1
• FLJ34050
• FLJ41900
• homolog of secretory protein SEC7
• PH, SEC7 and coiled-coil domain-containing protein 1
• pleckstrin homology, Sec7 and coiled-coil domains 1
• PSCD1
• SEC7 homolog B2-1
• SEC7

Background

Pleckstrin homology, Sec7 and coiled/coil domains 1 (PSCD1) is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The PSCD1 is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. PSCD1 protein is 83% homologous to PSCD2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CYTH1