Cyr61/CCN1 Antibody (3A7.1B8)

Images

 
Western Blot: Cyr61/CCN1 Antibody (3A7.1B8) [NBP2-36490] - WB analysis of (A) 12kDa Partial Recombinant Cyr61/CCN1 protein and (B) Human Liver lysate using Cyr61/CCN1 antibody (clone 3A7.1B8) at 4ug/ml concentration.
Immunohistochemistry-Paraffin: Cyr61/CCN1 Antibody (3A7.1B8) [NBP2-36490] - IHC analysis of formalin-fixed paraffin-embedded tissue section of human liver using Cyr61/CCN1 antibody (clone 3A7.1B8) at 5 ug/ml ...read more
Immunohistochemistry-Paraffin: Cyr61/CCN1 Antibody (3A7.1B8) [NBP2-36490] - IHC analysis of formalin-fixed paraffin-embedded tissue section of human hepatocellular carcinoma using Cyr61/CCN1 antibody (clone 3A7.1B8) at ...read more
Immunohistochemistry-Paraffin: Cyr61/CCN1 Antibody (3A7.1B8) [NBP2-36490] - IHC analysis of formalin-fixed paraffin-embedded tissue section of human Renal Cell Carcinoma using Cyr61/CCN1 antibody (clone 3A7.1B8) at 5 ...read more

Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications WB, IHC, IHC-P
Clone
3A7.1B8
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Cyr61/CCN1 Antibody (3A7.1B8) Summary

Immunogen
Partial recombinant protein from human Cyr61/CCN1 protein (between residues 100-300). [Swiss-Prot O00622]
Localization
Secreted (Cytoplasmic/Extracellular)
Predicted Species
Primate (100%). Backed by our 100% Guarantee.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CCN1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 4 ug/ml
Application Notes
Protein CYR61 is a secreted protein and its expected immunolocalization would be cytoplasmic as well as the extracellular spaces.

Reactivity Notes

Immunogen's sequence similarity with other species: Rat (81%), Mouse (79%), Camel (88%), Naked Mole Rat (87%), Porcine (80%), Bovine / Sheep / Horse (82%), Chicken (63%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for Cyr61/CCN1 Antibody (3A7.1B8)

  • CCN family member 1
  • CCN1
  • CCN1IGF-binding protein 10
  • Cyr61
  • Cysteine-rich angiogenic inducer 61
  • cysteine-rich, angiogenic inducer, 61
  • GIG1
  • GIG1cysteine-rich heparin-binding protein 61
  • IBP-10
  • IGFBP-10
  • IGFBP10cysteine-rich, anigogenic inducer, 61
  • Insulin-like growth factor-binding protein 10
  • protein CYR61
  • Protein GIG1

Background

Cysteine-rich angiogenic inducer 61, also known as CYR61, is a growth factor-inducible, immediate-early gene that has multifaceted activities in various cancers. CYR61 is a secreted heparin-binding extracellular matrix-associated protein whose activities include the promotion of adhesion and chemotaxis, and the stimulation of fibroblast and endothelial cell growth. CYR61 induces angiogenesis and promotes tumor growth and is expressed in dermal fibroblasts during cutaneous wound healing.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-36490AF350
Alexa Fluor 405 NBP2-36490AF405
Alexa Fluor 488 NBP2-36490AF488
Alexa Fluor 532 NBP2-36490AF532
Alexa Fluor 594 NBP2-36490AF594
Alexa Fluor 647 NBP2-36490AF647
Alexa Fluor 700 NBP2-36490AF700
Alexa Fluor 750 NBP2-36490AF750
Biotin NBP2-36490B
DyLight 350 NBP2-36490UV
DyLight 405 NBP2-36490V
DyLight 488 NBP2-36490G
DyLight 550 NBP2-36490R
DyLight 594 NBP2-36490DL594
DyLight 650 NBP2-36490C
DyLight 680 NBP2-36490FR
DyLight 755 NBP2-36490IR
FITC NBP2-36490F
HRP NBP2-36490H
Janelia Fluor 549 NBP2-36490JF549
Janelia Fluor 646 NBP2-36490JF646

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Bioinformatics

Gene Symbol CCN1
Entrez
Uniprot