CSN1 Antibody

Images

 
Biological Strategies: Western Blot: CSN1 Antibody [NB100-362] - Detection of Human CSN1 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa and 293T cells prepared using NETN lysis buffer. Antibodies: ...read more
Immunohistochemistry: CSN1 Antibody [NB100-362] - Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-CSN1 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB
Biological Strategies: Western Blot: CSN1 Antibody [NB100-362] - Whole cell lysate (50 ug - E; 10 ug - T) from mock transfected (E) or CSN1 transfected (T) HEK293T cells. Antibody used at the indicated ...read more
Biological Strategies: Western Blot: CSN1 Antibody [NB100-362] - Samples : Whole cell lysate (50 ug - E; 10 ug - T) from mock transfected (E) or CSN1 transfected (T) HEK293T cells. Antibody : Affinity purified ...read more
Immunohistochemistry-Paraffin: CSN1 Antibody [NB100-362] - FFPE section of human prostate-nodular hypertrophy. Affinity purified rabbit anti-CSN1 used at a dilution of 1:250. Detection: DAB staining using ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml
Validated by:
   

Biological Strategies

     

Order Details

CSN1 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 400 and the C-terminus (residue 471) of human G protein Pathway Suppressor 1 using the numbering given in Swiss-Prot entry Q13098 (GeneID 2873).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GPS1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000-1:10000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:500- 1:2000
Application Notes
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.
Publications
Read Publication using NB100-362.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CSN1 Antibody

  • COP9 signalosome complex subunit 1
  • COPS1JAB1-containing signalosome subunit 1
  • CSN1MGC71287
  • G protein pathway suppressor 1SGN1
  • GPS-1
  • Protein MFH
  • Signalosome subunit 1

Background

COP9 signalosome is a conserved protein composed of eight subunits. Individual subunits of the complex have been linked to various signal transduction pathways leading to gene expression and cell cycle control. CSN1 is the COP9 subunit 1. The C-terminus of CSN1 is responsible for interacting with CSN2, CSN3, and CSN4 subunits. It is required for incorporation of the subunit into the complex. The N-terminus harbors the activity domain that confers most of the repression functions of CSN1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CSN1 Antibody (NB100-362)(1)

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Bioinformatics

Gene Symbol GPS1
Entrez
Uniprot