CRMP5 Antibody (CR-1)

Images

 
Immunohistochemistry-Paraffin: CRMP5 Antibody (CR-1) [NB100-74395] - Biopsies of deparaffinized Human glioma tissue.
Immunohistochemistry-Paraffin: CRMP5 Antibody (CR-1) [NB100-74395] - Biopsies of deparaffinized Human brain tissue.

Product Details

Summary
Reactivity Hu, Rt, BvSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-Fr, IHC-P
Clone
CR-1
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated

Order Details

CRMP5 Antibody (CR-1) Summary

Immunogen
CRMP5 protein purified from human brain.
Specificity
CRMP5 (CR-1)
Isotype
IgG1
Clonality
Monoclonal
Host
Rat
Gene
DPYSL5
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000 - 1:2000
  • Immunocytochemistry/Immunofluorescence 2 - 3 ug/mL
  • Immunohistochemistry 1:2000
  • Immunohistochemistry-Frozen 1:2000
  • Immunohistochemistry-Paraffin 1:2000
Application Notes
WB: Detects an approx. 62 kDa protein representing human CRMP5 from brain extract.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Ascites
Preservative
0.05% Sodium Azide
Purity
Unpurified

Alternate Names for CRMP5 Antibody (CR-1)

  • Collapsin response mediator protein 5
  • collapsin response mediator protein-5
  • CRAMCRMP3-associated molecule
  • CRMP-5FLJ45383
  • CRMP5UNC33-like phosphoprotein 6
  • dihydropyrimidinase-like 5
  • dihydropyrimidinase-related protein 5
  • DRP-5
  • Ulip6
  • ULIP-6

Background

The collapsin response mediator protein (CRMP) family of proteins (also referred to as ULIP6) are a group of neurologic proteins that have been found to play key roles in growth cone guidance during neural development. CRMP5 has relatively low sequence homology with the other four members of the CRMP family. CRMP5 is expressed in the developing nervous system in an expression pattern that resembles CRMP2 and has a peak expression during the first postnatal week. Elevated levels of autoantibody to CRMP5 have been shown to be linked paraneoplastic autoimmune optic neuritis and other paraneoplastic neoplasms. Auto-immunity against CRMP5 expression (predominantly the N-terminal epitopes) is also being investigated as an oncological marker in the respiratory system and in the thymus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol DPYSL5
Entrez