CPT1B Antibody

Immunohistochemistry-Paraffin: CPT1B Antibody [NBP1-84389] - Staining of human heart muscle shows strong cytoplasmic positivity in myocytes.

Product Discontinued

CPT1B Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: KLWLYEGARLLKPQDLEMQFQRILDDPSPPQPGEEKLAALTAGGRVEWAQARQAFFSSGKNKAALEAIERAAFFVALDEESYSYDPEDEASLSLYGKALLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTD
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CPT1B
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (87%), Rat (86%)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for CPT1B Antibody

• carnitine O-palmitoyltransferase 1, muscle isoform
• carnitine O-palmitoyltransferase I, mitochondrial muscle isoform
• Carnitine O-palmitoyltransferase I, muscle isoform
• carnitine palmitoyltransferase 1B (muscle)
• Carnitine palmitoyltransferase 1B
• Carnitine palmitoyltransferase I-like protein
• CPT I
• CPT1B
• CPT1M
• CPT1-M
• CPT1-MMCCPT1
• CPTI
• CPTI-M
• EC 2.3.1
• EC 2.3.1.21
• FLJ55729
• FLJ58750
• KIAA1670
• MCPT1
• M-CPT1

Background

The protein encoded by the CPT1B gene, a member of the carnitine/choline acetyltransferase family, is the rate-controllingenzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the nettransport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variantsencoding different isoforms have been found for this gene, and read-through transcripts are expressed from theupstream locus that include exons from this gene. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CPT1B