COX-2 Antibody (SP21)

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Immunohistochemistry-Paraffin: COX-2 Antibody (SP21) [NBP1-49796] - Human Breast Carcinoma

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC, IHC-P
Clone
SP21
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

COX-2 Antibody (SP21) Summary

Immunogen
Synthetic peptide corresponding to C-terminus of rat COX2.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
PTGS2
Purity
Tissue culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
This product is useful for Immunohistochemistry Paraffin. Antigen retrieval can be performed using a Citrate process.
Publications
Read Publication using
NBP1-49796 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS (pH 7.5) and 1.0% BSA
Preservative
0.1% Sodium Azide
Purity
Tissue culture supernatant

Notes

For a positive control use Breast carcinoma.

Alternate Names for COX-2 Antibody (SP21)

  • COX2
  • COX-2
  • COX2cyclooxygenase 2b
  • cyclooxygenase-2
  • EC 1.14.99
  • EC 1.14.99.1
  • GRIPGHS
  • hCox-2
  • PGG/HS
  • PGH synthase 2
  • PGHS-2
  • PHS II
  • PHS-2
  • PHS-II
  • prostaglandin G/H synthase 2
  • prostaglandin G/H synthase and cyclooxygenase
  • Prostaglandin H2 synthase 2
  • prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase andcyclooxygenase)
  • Prostaglandin-endoperoxide synthase 2
  • PTGS2

Background

COX2 (Cyclooxygenase-2. PGHS2) is an inducible dimeric enzyme belonging to prostaglandin G/H synthase family. COX2, similar to COX1, functions to form prostaglandins by catalyzing the synthesis of cyclic endoperoxides from arachidonic acid. COX2 expression is induced by lipopolysaccaride (LPS) and peptoglycan (PGN) and is highly expressed in activated marcophages. It has been implicated as a mediator of inflammation and a possible role in prostanoid signaling in activity-dependent plasticity (1). COX2 is considered as an ideal marker in immune response regulation studies and a therapeutic target against inflammatory diseases (2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for COX-2 Antibody (NBP1-49796)(1)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: IHC-P.


Filter By Application
IHC-P
(1)
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Mouse
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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PTGS2
Entrez